Enrollment is closed
  • End of Registration
  • Registration closed
  • Classes Start
  • feb 25 2019
  • Classes End
  • may 05 2019
  • Estimated Effort
  • 1 h/week
  • Language
  • English

About the course

After a brief introduction on the physical basis of radioactivity, the MOOC "at the heart of medical radioactivity", will present in different stages the interest of medical radioactivity, from the design of a radiopharmaceutical to its use in the patient. The public objective of this MOOC is to demonstrate the medical use of radioactivity and its modalities.


This course lasts 6 weeks (including an introductory week) and is divided into 24 sequences. Each week 2 to 6 thematic sequences will be discussed. The sequences will be presented in the form of videos, and participants will have access to additional documents to better understand or deepen understanding of certain concepts. Participants will also have suggestions for additional lessons or videos to view (outside the FUN platform).


Consumer Scientific MOOC: There are no mandatory prerequisites to using and understanding this MOOC. Nevertheless, a high school level of scientific understanding will make it easier to understand some technical concepts discussed in the courses, especially in the advanced levels of knowledge presented.


Caroline Bodet-Milin

Caroline Bodet-Milin is a physician in the nuclear medicine department of the University Hospital of Nantes and on the PETSCAN platform of IRCNA. She is also a senior lecturer in biophysics-nuclear medicine and a researcher in the nuclear oncology group of INSERM UMR 1232 unit, and studies radioimmunotherapy and phenotypic imaging in nuclear medicine.

Mickaël Bourgeois

Mickaël Bourgeois is a radiopharmacist at Nantes University Hospital and the ARRONAX cyclotron. He is also a lecturer in biophysics and a researcher in the nuclear oncology group of the INSERM UMR 1232 unit, and studies radioimmunotherapy and phenotypic imaging in nuclear medicine.

Course plan

  • Week 0 : Introduction to the MOOC
    • Ep#1: History of Nuclear Medicine 
    • Ep#2: Medical use of ionizing radiation
  • Week 1 : What is Radioactivity?
    • Ep#1: Journey to the heart of matter
    • Ep#2: The Origins of Radioactivity
    • Ep#3: The Different Types of Radioactivity
    • Ep#4: Concepts in Radiobiology
  • Week 2 : Production of Radioactive Isotopes
    • Ep#1: Cyclotron production: The example of fluorine-18
    • Ep#2: Cyclotron production: The example of Astatine-211
    • Ep#3: The Neutron Reactor: Example of iodine-131 production
    • Ep#4: Generator production: Example of metastable Technetium-99
  • Week 3 : Radiopharmaceuticals: Definition and Mode of Action
    • Ep#1: What is a radiopharmaceutical?
    • Ep#2: How radiopharmaceuticals work: The concept of molecular targeting
    • Ep#3: Radiopharmaceuticals for diagnostic applications
    • Ep#4: Radiopharmaceuticals for Therapeutic Applications
  • Week 4 : Medical Applications
    • Ep#1: Patient pathway - Diagnostic tests in conventional nuclear medicine: an example of bone and myocardial scintigraphy
    • Ep#2: Patient pathway - Diagnostic Tests using Positron Emission Tomography: Example of FDG PET
    • Ep#3: Patient pathway - Therapeutic Applications: An Example of Iodine-131 radiotherapy
    • Ep#4: Contribution of nuclear medicine to personalized medicine
    • Ep#5: Contribution of Nuclear Medicine in the management of breast cancer
    • Ep#6: Use of ionizing radiation in external radiotherapy
  • Week 5 : Radioprotection
    • Ep#1: Radiation protection: Regulatory framework and theoretical data
    • Ep#2: Practical radiation protection
    • Ep#3: Perception of radioactivity, theoretical data
    • Ep#4: The hospitalization experience in a shielded room of patients with thyroid cancer treated with iodine-131


In order to estimate the participants' understanding of the contents of thematic sequences, quizzes in the form of multiple choice questions will be carried out at the end of each sequence. A successful follow-up certificate may be issued at the end of the MOOC depending on the results of the quizzes.


Agence Nationale de la Recherche


CHU de Nantes

Conditions of use

Terms of use of the course

Restrictive license

The contents of the MOOC can not be reused outside the FUN platform without the explicit agreement of the University of Nantes.

Terms of use for content produced by users

Restrictive license

The production of the MOOC can not be reused outside the FUN platform without the explicit agreement of their authors