Viral Hepatitis
Ref. 96017
- Duration: 6 weeks
- Effort: 18 hours
- Pace: ~3 hours/week
In this MOOC, you will find the latest developments on the intimate structure and pathophysiology of hepatic viruses, as well as the epidemiology and clinical courses of hepatitis.
No open course runs
What you will learn
At the end of this course, you will be able to:
- Summarize the virology and pathophysiology of the five differents viruses
- Describe the epidemiology and diseases progression
- Define recent progresses in vaccines and efficient treatments
- Explain why too few people have access to screening and treatments
- Discuss how WHO expects to eradicate viral hepatitis by 2030
Description
Hepatitis is an acute or chronic inflammation of the liver. Viral Hepatitis are very common worldwide, mainly caused by five different viruses (Hepatitis A, B, C, D and E). Mortality is related mainly to chronicity leading to fibrosis, cirrhosis and liver cancer. This occurs mostly for hepatitis B, B-D and C, viruses transmitted by blood and reaching mainly drug users, inmates and men having sex with men.
The mortality of viral hepatitis remains high through the world (1.6 million death in 2016 according to WHO) particularly since access to screening, prevention and efficient medications remains critically low in many developping countries, but not only.
In this MOOC, you will find the latest developments on the intimate structure and pathophysiology of hepatic viruses, as well as the epidemiology and clinical courses of hepatitis.You will learn about prevention of hepatitis A, B by immunization and about the most recent developments of efficient treatments of hepatitis B and hepatitis C. Finally, you will learn about the many public health issues of viral hepatitis and the ambitious plan of WHO to eradicate viral hepatitis by 2030.
Format
This MOOC is organized in 6 chapters, each module is composed of 2 to 9 sessions. In each session, you will find a 8-10-minute video and a multiple choice test to help you check your understanding. The videos are in English subtitled in French and in English.
Prerequisites
This MOOC aims to reach anybody who wishes to learn more about emerging viruses and pandemics, whether scientist, medical doctor or other health workers, staff of governmental and non-governmental agencies or students in life sciences.
We recommend a good scientific background (such as a bachelor of life science)
Assessment and certification
To follow this course, you have the choice between two formulas. The DISCOVERY path gives you access to videos, quizzes and exchanges in the forum. Additionnaly, the QUALIFYING path gives you access to a qualifying exam.
- Discovery path
If you opt for this path, you will have access to the videos, the quizzes and the exchanges in the forum. For this path, no certificate will be delivered. The registration is free.
- Qualifying path
In addition to the activities offered in the DISCOVERY path, the QUALIFYING formula will allow you to obtain a certificate in the form of a "certificate". To do this, you will have to take a exam, monitored remotely, lasting 1 hour, consisting of 30 multiple choice questions (MCQ) and obtaining 18 correct answers.
The registration fee for the qualifying course is 150€.
Obtaining a qualifying certification is an opportunity for you to obtain a diploma. This course is one of the MOOCs of the Institut Pasteur's Digital Diploma in Infectious Diseases program (DNM2IP). For more information, see the Institut Pasteur web page, dedicated to this new diploma
Course plan
- C1-1: Generalities on hepatitis viruses
C1-2: Natural history of viral hepatitis
C1-3: Evaluation of fibrosis in patients with chronic hepatitis : non invasive tests
C1-4: Viral hepatocarcinogenesis
C1-5: Specific features related to populations and continents
C1-6: Co-infections in patients with viral hepatitis
- C2-1 : Hepatitis A virus : pathophysiology, virological diagnosis and follow-up of HAV infection
C2-2 : Epidemiology and natural history of hepatitis A
- C3-1: Virology and pathophysiology of hepatitis B virus
C3-2: Hepatitis B infection virological diagnosis
C3-3: Epidemiology of viral hepatitis B
C3-4: Natural history and complications of viral hepatitis B
C3-5: Hepatitis D virus : pathophysiology and virological diagnosis
C3-6: Natural history of hepatitis D
C3-7: Viral hepatitis B in Africa
C3-8: Treatment of viral hepatitis B and B-D
C3-9: Vaccination against HBV
- C4-1: Virology of hepatitis C virus and pathophysiology
C4-2: Epidemiology of viral hepatitis C
C4-3: Hepatitis C infection virological diagnosis
C4-4: Natural history and complications of viral hepatitis C
C4-5: Peculiarities of hepatitis C in Asia
C4-6: Treatment of hepatitis C
C4-7: where are we up to with HCV vaccination ?
- C5-1: Hepatitis E virus and pathophysiology of infection by HEV
C5-2: Epidemiology, natural history, complications and treatment of viral hepatitis E
C5-3: Differential diagnosis of non alphabetical hepatitis
- C6-1: Viral hepatitis screening
C6-2: Mother-to-child transmission
C6-3: Public health issues of hepatitis in developped countries
C6-4: Management of treated and untreated patients with hepatitis
C6-5: HBV cure
C6-6: HCV elimination
C6-7: Prioritization of the initiatives for the WHO Elimination program
Course runs
Archived
- From May 11, 2020 to July 8, 2020
- From May 10, 2022 to July 9, 2022
Course team
FRANÇOISE LUNEL-FABIANI
Categories
Professor of Microbiology
Professor at Université d’Angers and Head of the Microbiology Department in the University Hospital
Stanislas Pol
Categories
Professor of Hepatology and Gastroenterology at Université Sorbonne Paris Cité, Paris, France.
Dominique Franco
Categories
Emeritus professor of digestive surgery and special advisor to the Education Department of the Institut Pasteur where he completed 20 MOOCs.
Organizations
License
License for the course content
Attribution-NonCommercial-ShareAlike
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
License for the content created by course participants
Attribution-NonCommercial-ShareAlike
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.