Rabies
Ref. 96023
This course explains the pathophysiology, epidemiology, vaccines and elimination strategies of the rabies virus.
- Duration: 9 weeks
- Effort: 29 hours
- Pace: ~3h15/week
- Languages: English, french and portuguese
What you will learn
At the end of this course, you will be able to:
- Explain the transmission, symptoms and clinical management of rabies
- Specify the importance of different animal reservoirs in the spread of the virus
- Describe human and animal vaccination strategies to combat rabies virus
- Identify the role of international organizations in rabies elimination
- Discuss rabies control strategies in different regions of the world
Description
Rabies is a fatal encephalitis caused by a Lyssavirus primarily transmitted by the bite or scratch of infected animals. Despite efforts in recent years, an estimated 60,000 human deaths from rabies still occur each year worldwide, primarily in Asia and Africa. This is due to a lack of awareness, inaccessibility of post-exposure prophylaxis for exposed individuals, inadequate or non-existent canine rabies control programs, and lack of financial support from governments.
The objective of this MOOC is to share the experiences and knowledge of international experts in animal and human public health on rabies. The course emphasizes the need for a multidisciplinary approach and "One Health" intersectoral cooperation for effective rabies control and elimination.
Format
This MOOC is composed of 7 teaching chapters. Each chapter has 2 to 5 sequences. Each sequence consists of a video of about 10 minutes and a MCQ so that students can test their knowledge. The videos are in English with French, Portuguese and English subtitles.
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Prerequisites
This MOOC is open to anyone interested in rabies, with a good scientific background. A scientific degree is recommended to follow this MOOC.
Required Equipment
You will need a computer with a browser and sound, as well as a sufficient internet connection to follow the MOOC.
Assessment and certification
To follow this course, you can choose between two options:
- The Discovery Course gives access to videos, quizzes and discussions in the forum. No badge is issued for this course. Registration is free.
- The Qualifying Course leads to a certificate. In addition to the activities of the Discovery Course, you will have to take a one-hour supervised distance learning exam, consisting of 30 multiple-choice questions (MCQs) and obtaining 18 correct answers. The registration fee for the Qualifying Course is 150€.
Successful completion of the Qualifying Course gives you the opportunity to apply for the Institut Pasteur Online Diploma of Infectious Diseases (DNM2IP), which consists of 5 certificates to Institut Pasteur MOOCs on infectious diseases. To learn more, visit the Institut Pasteur's web page dedicated to this diploma.
Accessibility
The videos in the MOOC are all subtitled, in both English and French. Their playback speed can be accelerated or slowed down to suit your needs.
The subtitles are also grouped together in a text format for each video: these are the transcripts, accessible under each video.
Finally, more and more MOOCs also include what we call the BOOC. This is a PDF document containing all the transcripts, to which images and diagrams have been added to aid understanding. The BOOC can be downloaded.
Course plan
- • C1.1 : General introduction and history / Hervé BOURHY (IPP, France)
• C1.2 : Rabies virus and lyssaviruses: structure, replication, virus-host cell interactions / Noel TORDO (IPGui, Guinea)
- • C2.1 : Rabies in dogs / Jesse BOMWITT (Durham University - UK)
• C2.2 : Rabies in humans / Beatriz QUIAMBAO (Research Institute for Tropical Medicine (RITM), the Philippines)
• C2.3 : Diagnosis in animals / Paola DE BENEDICTIS (IZSVe, Italy)
• C2.4 : Diagnosis in humans / Laurent DACHEUX (IPP, France)
- • C3.1 : Dog ecology and role of the dogs as main reservoir of rabies / Véronique CHEVALIER (CIRAD/IPM, Madagascar)
• C3.2 : Role of wildlife carnivores / Cécile TROUPIN (IPC, Cambodia)
• C3.3 : Role of bats, Jordi SERRA-COBO (University of Barcelona, Spain)
• C3.4 : Global epidemiology of human rabies / Katie HAMPSON (University of Glasgow, UK)
- • C4.1 : Anti-rabies immune responses / Tineke CANTHAERT (IPC, Cambodia)
• C4.2 : Human rabies vaccines / Lucille BLUMBERG (University of Pretoria, South Africa)
• C4.3 : Animal rabies vaccines / Ryan WALLACE (CDC, USA)
• C4.4 : Vaccination in humans (pre- and post-exposure) / Arnaud TARANTOLA (Santé Publique France, France)
• C4.5 : Implementation of PEP in developing countries: the example of Cambodia / Sowath LY (IPC, Cambodia)
• C4.6 : Vaccination in dogs / Florence CLIQUET (ANSES, France)
• C4.7 : Rabies control strategies at the example of Africa / Jakob ZINSSTAG (Swiss TPH, Switzerland)
- • C5.1 : Development of new rabies vaccines / Charles RUPPRECHT (LYSSA LLC, USA)
• C5.2 : Drugs strategies / Noel TORDO (IPGui, Guinea)
• C5.3 : Monoclonal antibodies / Hervé BOURHY (IPP, France)
- • C6.1 : As we step closer: The “Zero by 30” rabies elimination strategy / Bernadette ABELA-RIDDER (WHO, Switzerland)
• C6.2 : The role of international organisations in reaching “Zero by 30” / Rachel TIDMAN (OIE, France)
• C6.3 : Work of the Food and Agriculture Organisation of the United Nation (FAO) on Rabies: Contributing to “0 by 30” / Katinka De Balogh (FAO, Italy)
• C6.4 : Communication and community participation / Louis NEL (GARC, South Africa)
- • C7.1: Oral vaccination from foxes to dogs / Thomas MULLER (FLI, Germany)
• C7.2: Rabies situation in the Americas / Marco VIGILATO (PAHO, USA)
• C7.3 : Rabies situation in India and elimination issues in Asia / Reeta S. MANI (NIMHANS, India)
• C7.4: Example of Morocco / Oussama DEHHANI (ONSSA, Morocco)
• C7.5: Example of KwaZulu- Natal, South Africa / Kevin LEROUX (Kwazulu Natal Department of Agriculture, South Africa)
Course team
Hervé Bourhy
Categories
MOOC Director - Prof. Hervé Bourhy heads the Global Health Department, the Lyssavirus, Epidemiology and Neuropathology Laboratory, the WHO Collaborating Center for Rabies Reference and Research and the National Reference Center for Rabies at the Institut Pasteur, Paris, France.
Noël Tordo
Categories
MOOC Director - Dr. Noël Tordo, Director of the Institut Pasteur de Guinée, Member of the Board of the Pasteur Network, President of the French Society for Virology.
Cécile Troupin
Categories
MOOC Coordinator - Doctor in virology, I have been working on rabies in the Pasteur Network for 10 years. I am currently in charge of the Medical Virology and Rabies group at the Pasteur Institute of Laos.
Perrine PARIZE
Categories
Community manager - Perrine is a medical doctor and deputy director at the French National Reference Center for Rabies at the Institut Pasteur, Paris.
Guilherme DIAS DE MELO
Categories
Community manager of Rabies MOOC - Guilherme Dias de Melo is a member of the Lyssavirus, Epidemiology and Neuropathology unit at the Institut Pasteur, Paris, France, where he works with rabies and other neurotropic viruses and virus-induced neurobehavioral disorders.
Organizations
License
License for the course content
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
License for the content created by course participants
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.