Innate Immunity

What you will learn

At the end of this course, you will be able to:

Define the cellular and molecular players of innate immunity,
Describe the mechanisms that lead to the elimination of pathogens
Explain the strategies of the pathogens against the innate immune system
Discuss the influence of genetic and microbiota on innate immune system
Present its links with central nervous system and adaptive immunity

Description

Innate immunity acts as a first line of defense and can destroy invading microorganisms and trigger inflammation that contributes to blocking their assault, days before the action of adaptive immunity. While adative immunity was the major focus of researchers in the XXth century, the sensing of the exogenous or endogenous dangers signals was recently described, as well of the action of numerous cells. This MOOC describes the players and the whole orchestra involved in innate immunity against pathogens.

Format

This MOOC is organized in 6 chapters. Each chapter is composed of 4 to 7 sequences. In each sequence, you find a 10 minute video and a multiple choice test to help students check their understanding. The videos are in English subtitled in French and in English.

Prerequisites

This MOOC targets people with a medical or scientific training background who are interested in all aspects of innate immunity: medical students, scientific Master II and PhD students (Immunology, Bacteriology, Parasitology, Virology…), post-doc, physicians, pharmacists, veterinarians, and all scientists working on bacteria, viruses, fungi and parasites, interested to learn more about the defense mechanism of the host against their favored bug.

Assessment and certification

You may register to this MOOC in two ways:

Discovery path.

You get access to all video-sessions, post session and weekly quizzes and web-forum.

Qualifying path.

In addition to video-sessions, post session and weekly quizzes and web-forum, you have access to hangouts along the MOOC and to a final individual online evaluation under surveillance.
Success at this final examination will provide you with a certificate signed by FUN and by Institut Pasteur.
The cost of the qualifying course is 150€.
Before registering to the qualifying path make sure that your scientific background is sufficient enough and correspond at least to a bachelor of live sciences.

To qualifying path, success at this final examination will provide you with a certificate signed by FUN and by Institut Pasteur.

Course plan

Chapter 1: Cellular players - part 1
Chapter 2: Cellular players - part 2
Chapter 3: Molecular players - part 1
Chapter 4: Molecular players - part 2
Chapter 5: Host-pathogen interactions
Chapter 6: Regulation of innate immune response

Course runs

Archived

From May 2, 2017 to June 12, 2017
From Nov. 4, 2019 to May 1, 2020
From Jan. 14, 2022 to March 16, 2022

Course team

Jean-Marc Cavaillon

Daniel Scott-Algara

Organizations

Institut Pasteur

License

License for the course content

Attribution-NonCommercial-NoDerivatives

You are free to:

Share — copy and redistribute the material in any medium or format

Under the following terms:

Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.