Biobanking
Ref. 96019
Organizational, technical, scientific, legal, ethical aspects of biobanks are reviewed.
- Duration: 8 weeks
- Effort: 24 hours
- Pace: ~3 hours/week
- Languages: English and french
What you will learn
At the end of this course, you will be able to:
- Understand how biobanks allow end-users to access fit-for-purpose biological resources
- Be aware of the ethical, regulatory and quality assurance aspects of processing, preservation and distribution of biological resources
- Learn about validation of biobank methods
- Get to know international networks of biobanks
Description
Biobanks are entities ensuring the management and preservation of biological resources, such as biological fluids or tissues of human origin, living cells, microbes, and their associated data. The major objective of biobanks is to preserve these resources in optimal conditions to maintain their integrity and make them available to the scientific community to both advance research and knowledge worldwide, and facilitate the identification of biomarkers and the development of innovative drugs, vaccines or diagnostic tests.
In this MOOC, different aspects of acquisition, processing, and preservation of different types of biological resources are discussed. Specificities of human and microbial biobanking are mentionned. Several sessions are devoted to the quality assurance of these biobanks to meet international standards.
Format
This MOOC is composed of 4 teaching chapters, the first on general considerations, the second on biospecimen and data science and the third on international, legal and ethical issues, and finally, the fourth on practical examples. Each chapter has 4 to 7 sequences. Each sequence consists of videos of 10-20 minutes and a MCQ so that students can test their knowledge. The videos are in English with French, spanish and English subtitles.
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Prerequisites
This MOOC is aimed at undergraduate, graduate and PhD biology students, medical doctors, teachers, researchers and all those who want to learn what are biobanks and how they have to be managed. A good scientific background is recommended to follow this MOOC.
Required Equipment
You will need a computer with a browser and sound, as well as a sufficient internet connection to follow the MOOC. The use of a camera is compulsory for the examination.
Assessment and certification
To follow this course, you can choose between two options:
- The Discovery Course gives access to videos, quizzes and discussions in the forum. No badge is issued for this course. Registration is free.
- The Qualifying Course leads to a certificate. In addition to the activities of the Discovery Course, you will have to take a one-hour supervised distance learning exam, consisting of 30 multiple-choice questions (MCQs) and obtaining 18 correct answers. The registration fee for the Qualifying Course is 150€.
Successful completion of the Qualifying Course gives you the opportunity to apply for the Institut Pasteur Online Diploma of Infectious Diseases (DNM2IP), which consists of 5 certificates to Institut Pasteur MOOCs on infectious diseases. To learn more, visit the Institut Pasteur's web page dedicated to this diploma.
Accessibility
The videos in the MOOC are all subtitled, in both English and French. Their playback speed can be accelerated or slowed down to suit your needs.
The subtitles are also grouped together in a text format for each video: these are the transcripts, accessible under each video.
Finally, more and more MOOCs also include what we call the BOOC. This is a PDF document containing all the transcripts, to which images and diagrams have been added to aid understanding. The BOOC can be downloaded.
Course plan
- C1-1: Definitions and introduction, what is a biobank ? / Fay Betsou
- C1-2: Why biobanks are important? / Fay Betsou
- C1-3: Biospecimens and research reproducibility / Fay Betsou
- C1-4: Quality Management / Fay Betsou
- C1-5: Biobanks as processing laboratories / Fay Betsou
- C1-6: Presentation of the Biological Resource Center of Institut Pasteur (CRBIP) / Fay Betsou
- C1-7: Processing methods in biobanks, the example of fecal samples / Fay Betsou
- C2-1: Biospecimen Research / Fay Betsou
- C2-2: Validation and Verification of processing methods, / Fay Betsou
- C2-3: Validation and verification of processing methods, practice / Fay Betsou
- C2-4: Reference Materials / Fay Betsou
- C2-5: Data Management and quality at the Biological Resource Center of Institut Pasteur (CRBIP) / Mariana Ferrari
- C2-6: Example of Biobank Information Management System (BIMS) / Augusto Mantilla Ayala
- C3.1: International professional biobanking organisations / Fay Betsou
- C3-2: Standards and Standard Codes / Fay Betsou
- C3-3: Proficiency Testing for biobank laboratories / Fay Betsou
- C3-4: Legal aspects of biobanks / Fay Betsou
- C3-5: Nagoya Protocol / Raquel Hurtado-Ortiz
- C3-6: Transport of biological materials / Fay Betsou
- C3-7: Ethical issues / Fay Betsou
- C4-1: Presentation of the Institut Pasteur Collection (CIP) / Dominique Clermont
- C4-2: Methods of preserving fungi / Dirk Strubbe
- C4-3: Methods for cultivation and preservation of cyanobacteria / Muriel Gugger
- C4-4: Ethics in a health crisis -Ebola's lessons / Virginie Pirard
Course team
Fay BETSOU
Categories
Director of the MOOC, Fay is a biospecimen scientist with 25 year-long transdisciplinary experience in biobanking operations and applications.
Raquel HURTADO-ORTIZ
Categories
Community manager of the MOOC, Raquel is microbiologist and immunologist with experience in the management of Collections and Biobanks. She is the head of the National Collection of Cultures of Microorganisms (CNCM) at the Institut Pasteur, Paris.
Organizations
License
License for the course content
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
License for the content created by course participants
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.