Biobanking
Ref. 96019
Organizational, technical, scientific, legal, ethical aspects of biobanks are reviewed
- Duration: 8 weeks
- Effort: 24 hours
- Pace: ~3 hours/week
- Languages: English, french and spanish
What you will learn
At the end of this course, you will be able to:
- Understand how biobanks allow end-users to access fit-for-purpose biological resources
- Be aware of the ethical, regulatory and quality assurance aspects of processing, preservation and distribution of biological resources
- Learn about validation of biobank methods
- Get to know international networks of biobanks
Description
Biobanks are entities ensuring the management and preservation of biological resources, such as biological fluids or tissues of human origin, living cells, microbes, and their associated data. The major objective of biobanks is to preserve these resources in optimal conditions to maintain their integrity and make them available to the scientific community to both advance research and knowledge worldwide, and facilitate the identification of biomarkers and the development of innovative drugs, vaccines or diagnostic tests.
In this MOOC, different aspects of acquisition, processing, and preservation of different types of biological resources are discussed. Specificities of human and microbial biobanking are mentionned. Several sessions are devoted to the quality assurance of these biobanks to meet international standards.
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NOTA : El contenido del curso también está en español
Format
This MOOC is composed of 3 teaching chapters, the first on general considerations, the second on biospecimen and data science and the third on international, legal and ethical issues. Each chapter has 6 to 9 sequences. Each sequence consists of videos of 10-20 minutes and a MCQ so that students can test their knowledge. The videos are in English with French, spanish and English subtitles.
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Los videos están en inglés, con subtítulos en inglés, francés y español. Para los estudiantes que han elegido el examen de certificación, éste se puede realizar en inglés, francés o español.
Prerequisites
This MOOC is aimed at undergraduate, graduate and PhD biology students, medical doctors, teachers, researchers and all those who want to learn what are biobanks and how they have to be managed. A good scientific background is recommended to follow this MOOC.
Required Equipment
You will need a computer with a browser and sound, as well as a sufficient internet connection to follow the MOOC.
Assessment and certification
To follow this course, you can choose between two options:
- The Discovery Course gives access to videos, quizzes and discussions in the forum. No certificate is issued for this course. Registration is free.
- The Qualifying Course leads to a certificate. In addition to the activities of the Discovery Course, you will have to take a one-hour supervised distance learning exam, consisting of 30 multiple-choice questions (MCQs) and obtaining 18 correct answers. The registration fee for the Qualifying Course is 150€.
Successful completion of the Qualifying Course gives you the opportunity to apply for the Institut Pasteur Online Diploma of Infectious Diseases (DNM2IP), which consists of 5 certificates to Institut Pasteur MOOCs on infectious diseases. To learn more, visit the Institut Pasteur's web page dedicated to this diploma.
Accessibility
The videos in the MOOC are all subtitled, in both English and French. Their playback speed can be accelerated or slowed down to suit your needs.
The subtitles are also grouped together in a text format for each video: these are the transcripts, accessible under each video.
Finally, more and more MOOCs also include what we call the BOOC. This is a PDF document containing all the transcripts, to which images and diagrams have been added to aid understanding. The BOOC can be downloaded.
Course plan
- C1.1: Acquisition of microorganisms and its regulations - Joëlle Dupont (National Natural History Museum)
- C1.2: Description of a new bacterial species and control of its identity - Sylvain Brisse (Institut Pasteur)
- C1.3: Methods of preserving bacteria (lyophilization and freezing) - Dominique Clermont (Institut Pasteur)
- C1.4: Identification of fungi - Dea Garcia-Hermoso (Institut Pasteur)
- C1.5: Methods of preserving fungi - Dirk Stubbe (Sciensano)
- C1.6: Methods for cultivation and preservation of cyanobacteria - Muriel Gugger (Institut Pasteur)
- C1.7: Recruitment of volunteers for a human-sample biobank - Marie-Noelle Ungeheuer (Institut Pasteur)
- C1.8: Reparation and storage of human samples - Marie-Noelle Ungeheuer (Institut Pasteur)
- C1.9: Establishment of a viral biobank - Hervé Bourhy (Institut Pasteur)
- C2.1: Distribution of microorganisms and its regulations - Dominique Clermont (Institut Pasteur)
- C2.2: Biobanking and personalized medicine - Gianluca Severi (INSERM)
- C2.3: Distribution of human biological-samples: ethical and regulatory aspects - Amina Aït-Saadi (Institut Pasteur)
- C2.4: Procurement and contracts for biobanks - Matt McLoughlin (Scientist.com)
- C3.1: Health security and biobanks of infectious agents - Didier Houssin (APHP international)
- C3.2: The advantages of a Quality Management System - Nadine Ferey (Institut Pasteur)
- C3.3: GMOs and high-pathogenic microorganisms and toxins - Raquel Hurtado-Ortiz (Institut Pasteur)
- C3.4: Biobanking automation - Hélène Blanché-Koch (Fondation Jean Dausset)
- C3.5: IT tool for management and traceability - Laurent Swenson (Institut Pasteur)
- C3.6: Ethics in a health crisis - Ebola’s lessons - Virginie Pirard (Institut Pasteur)
- C4-1: Patents: International Depositary Authorities (IDAs) and the Budapest Treaty - Raquel Hurtado-Ortiz (Institut Pasteur)
- C4.2: Pharmaceutical applications of plant collections - Bruno David (Pierre Fabre)
- C4.3: Microbiome and conservation of microbial consortia - Mathieu Groussin (MIT)
- C4.4: Drug Discovery from Natural Products Libraries of Microbial Collections - Olga Genilloud (Fundación Medina)
- C4.5: Biobanks and diagnosis of infectious diseases - Jean Claude Manuguerra (Institut Pasteur)
Course team
Fay BETSOU
Categories
Director of the MOOC, Fay is a biospecimen scientist with 25 year-long transdisciplinary experience in biobanking operations and applications.
Raquel HURTADO-ORTIZ
Categories
Community manager of the MOOC, Raquel is chemist-bacteriologist-parasitologist and holds a master and a PhD degree in Immunology. Since 2018, she is the head of the National Collection of Cultures of Microorganisms (CNCM).
Organizations
Partners
French Embassy in Argentina
French Embassy in South Africa, Lesotho and Malawi
Ministry of Europe and Foreign Affairs
With the support of Fond de solidarité pour les projets innovants (FSPI)
License
License for the course content
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
License for the content created by course participants
Attribution-NonCommercial-NoDerivatives
You are free to:
- Share — copy and redistribute the material in any medium or format
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.